ELISHA Systems Ltd at the Biosensors World Congress in Glasgow, May 2010

08/Jun/2010

Dr Tim Gibson presented a poster at the Biosensors World Congress in Glasgow, Scotland in May 2010. A pdf of the poster is available here.

Commercialising impedance assay systems – the ELISHA platform

Dr Tim Gibson, Dr Graham Johnson and Prof Paul Millner
ELISHA Systems Ltd, Sigma House, Burlow Road, Buxton, SK17 9JB, UK. Telephone 01924 829560 E-mail timdgibson@merchab.fsnet.co.uk

A/C Impedance detection of target analytes using antibodies as the recognition element is a very topical research subject, with over 560 peer-reviewed papers being published in 2009 alone.

The technique is powerful and requires only the affinity binding between a primary antibody and its antigen to elicit a measurable signal. The principle requirement is to construct a nanoscale matrix that enables direct communication between the antibody and the underlying electrode to generate the signal to be measured.

The ELISHA project funded by the EU was the basis of the SME ELISHA Systems Ltd (ESL), who are working to transfer impedance technology from the research area into full commercial products.

ESL has World exclusivity to IP in the field of impedance interrogated antibody-conducting polymer sensors. Based on this technology platform, labeless electrochemical immunosensors have been constructed to a variety of target analytes.

The paper discusses the development of a range of different immunosensors and show results from a number of target analytes including fluoroquinoline antibiotics in whole milk, serogroup B menigococcus in whole blood and MRSA at 10-100 cells per ml.